Reproduction Abstracts

Until recently the mammalian oviducts or fallopian tubes were regarded as inert organs that provide a passive racecourse where spermatozoa compete against each other to reach the egg. Recent evidence suggests, however, that the female reproductive tract recognises the arrival of spermatozoa and initiates changes in gene expression and protein secretion profiles. We have observed that X- and Y-chromosome bearing spermatozoa alter gene expression in the maternal tract in differe...

Introduction: Embryo implantation is a complex and highly regulated process. Toll-Like receptors (TLRs) play a strategic role in recognition of pathogens in female reproductive tract. Activation of TLRs in endometrial cells at the time of embryo implantation appears to have negative effect on implantation. Tribbles-2 (Trib2) protein is members of tribbles family of psuedokinase proteins, modulating TLR5 signal transduction pathway.Tribbles-2 knockout female mice are infertile....

Introduction: The interaction of gametes and embryo with the maternal environment has a crucial impact on gametes maturation, embryonic development and subsequent pregnancy success. Recent studies have recognised extracellular vesicles (EVs) as a potent vehicles for intercellular communication. Defining the type of EVs which are produced by different reproductive cells will help us to understand how these structures can influence reproductive processes. The aim of the current ...